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Anti-FDPS Antibody (3H810)
还可以产品编号 TMAY-02549
Anti-FDPS Antibody (3H810) 是一种 Rabbit 抗体，靶向 FDPS。Anti-FDPS Antibody (3H810) 可用于 WB,IP。
Anti-FDPS Antibody (3H810)
Anti-FDPS Antibody (3H810)
还可以产品编号 TMAY-02549
Anti-FDPS Antibody (3H810) 是一种 Rabbit 抗体，靶向 FDPS。Anti-FDPS Antibody (3H810) 可用于 WB,IP。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-FDPS Antibody (3H810) is a Rabbit antibody targeting FDPS. Anti-FDPS Antibody (3H810) can be used in WB,IP. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3H810 |
| 交叉反应 | Human |
| 验证活性 | 1. FDPS was immunoprecipitated using: -Lane A:0.5 mg Raji Whole Cell Lysate. -2 µL anti-FDPS rabbit monoclonal antibody and 60 μg of Immunomagnetic beads Protein G. -Primary antibody: -Anti-FDPS rabbit monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 48 kDa. -Observed band size: 38 kDa. 2. Anti-FDPS rabbit monoclonal antibody at 1:500 dilution. -Lane A: HepG2 Whole Cell Lysate. -Lane B: Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:48 kDa. -Observed band size:38 kDa |
| 应用 | WB,IP |
| 推荐剂量 | WB: 1:500-1:2000; IP: 1-4 μL/mg of lysate |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human FDPS / Farnesyl Diphosphate Synthase (rh FDPS / Farnesyl Diphosphate Synthase; TMPY-02654; NP_001129294.1; Met1-Lys353). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions as key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate, a precurcor for several classes of essential metabolites. FDPS catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Functions of FDPS may be inactivated by interferon-induced RSAD2. This inactivation may result of disruption of lipid rafts at the plasma membrane, and thus have an antiviral effect since many enveloped viruses need lipid rafts to bud efficiently out of the cell. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human FDPS / Farnesyl Diphosphate Synthase protein (TMPY-02654) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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