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Anti-HDAC8 Antibody (7B830)

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货号 TMAB-06945

Anti-HDAC8 Antibody (7B830) 是一种 Rabbit 抗体,靶向 HDAC8。Anti-HDAC8 Antibody (7B830) 可用于 WB,ICC/IF,FCM。

Anti-HDAC8 Antibody (7B830)

Anti-HDAC8 Antibody (7B830)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06945

Anti-HDAC8 Antibody (7B830) 是一种 Rabbit 抗体,靶向 HDAC8。Anti-HDAC8 Antibody (7B830) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-HDAC8 Antibody (7B830) is a Rabbit antibody targeting HDAC8. Anti-HDAC8 Antibody (7B830) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
7B830
反应种属
Human
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Excluded from the nucleoli. Found in the cytoplasm of cells showing smooth muscle differentiation.
组织特异性Weakly expressed in most tissues. Expressed at higher level in heart, brain, kidney and pancreas and also in liver, lung, placenta, prostate and kidney.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
抗原信息
免疫原
A synthesized peptide: human HDAC8
抗原种属
Human
基因名称
HDAC8
基因ID
蛋白名称
Histone deacetylase 8
Uniprot ID
功能
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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