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Anti-GRP78 Antibody (7Y376)

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货号 TMAB-06798

Anti-GRP78 Antibody (7Y376) 是一种 Mouse 抗体,靶向 GRP78。Anti-GRP78 Antibody (7Y376) 可用于 WB。

Anti-GRP78 Antibody (7Y376)

Anti-GRP78 Antibody (7Y376)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06798

Anti-GRP78 Antibody (7Y376) 是一种 Mouse 抗体,靶向 GRP78。Anti-GRP78 Antibody (7Y376) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍


生物活性
产品描述
Anti-GRP78 Antibody (7Y376) is a Mouse antibody targeting GRP78. Anti-GRP78 Antibody (7Y376) can be used in WB.
Ig Type
IgG1, k
克隆号
7Y376
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of ~70 kDa heat shock proteins (HSP 70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and may associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins that are incorrectly folded, thus preventing their export from the ER lumen. GRP78 is a highly conserved protein that is essential for cell viability. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP 94) and protein disulfide isomerase (PDI). The presence of carboxy terminal KDEL appears to be necessary for retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
抗原信息
免疫原
Recombinant Protein: human HSPA5 between 420-654 amino acids
抗原种属
Human
基因名称
HSPA5
基因ID
蛋白名称
Endoplasmic reticulum chaperone BiP
Uniprot ID
功能
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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