SLAMF5 Protein, Human, Recombinant (His)

SLAMF5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-43 KDa and the accession number is Q9UIB8.

规格	价格/CNY		数量
10 μg	￥ 700	5日内发货
50 μg	￥ 1,970	5日内发货
500 μg	￥ 8,860	5日内发货
1 mg	￥ 12,600	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 700

5日内发货

50 μg

￥ 1,970

5日内发货

500 μg

￥ 8,860

5日内发货

1 mg

￥ 12,600

5日内发货

产品描述	SLAMF5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-43 KDa and the accession number is Q9UIB8.

种属	Human
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	Q9UIB8
别名	SLAMF5, Signaling lymphocytic activation molecule 5, Hly9-β, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, Hly9-beta
氨基酸序列	Lys22-Arg220
蛋白构建	Lys22-Arg220
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	35-43 KDa, reducing conditions

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of immune system function. Mature human CD84 consists of a 204 amino acid (aa) extracellular domain (ECD) with two Iglike domains,a 21 aa transmembrane segment, and a 99 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs (ITSMs). CD84 exhibits homophilic binding which is mediated by the N-terminal Ig-like domain. Ligation induces tyrosine phosphorylation in the cytoplasmic ITSMs which then recruit the signaling adaptor molecules SAP (SLAM-associated protein) and EAT-2(EWS/Fli1-activated transcript 2).CD84 signaling inhibits Fc epsilon RI-induced mast cell activation but enhances platelet activation. LPS-induced macrophage activation,T cell proliferation and IFN-γproduction, and the interactions between T cells and B cells that are required for germinal center formation.

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SLAMF5 Protein, Human, Recombinant (His)

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