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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SPESP1 Polyclonal Antibody

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货号 TMAB-13104

Anti-SPESP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SPESP1。Anti-SPESP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SPESP1 Polyclonal Antibody

Anti-SPESP1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13104

Anti-SPESP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SPESP1。Anti-SPESP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-SPESP1 Polyclonal Antibody is a Rabbit antibody targeting SPESP1. Anti-SPESP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Rat,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic vesicle > secretory vesicle > acrosome. Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome.
组织特异性Highly expressed in testis, where it is localized in the acrosome of postmeiotic stages of spermiogenesis (round and elongating spermatids and in ejaculated spermatozoa) (at protein level). Poorly expressed in placenta and fetal lung.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SPESP1 is a 399 amino acid protein belonging to the SPESP1 family. Localizing to cytoplasmic vesicle, secretory vesicle, and acrosome, SPESP1 is highly expressed in testis, with lower levels found in placenta and fetal lung. SPESP1 establishes an equatorial segment subcompartment early in sperm development and is required for proper sperm-egg fusion. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may interact with IZUMO1 and MN9 antigen and contains an N-glycosylation site as well as several cAMP-dependent kinase, protein kinase C, and casein kinase II consensus phosphorylation sites.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SPESP1
抗原种属
Human
基因名称
SPESP1
基因ID
246777
蛋白名称
Sperm equatorial segment protein 1
Uniprot ID
Q6UW49
功能
The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. [provided by RefSeq, Apr 2010]
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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