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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-Separase (Ser1073) Polyclonal Antibody

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货号 TMAB-11270

Anti-Phospho-Separase (Ser1073) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Separase (Ser1073)。Anti-Phospho-Separase (Ser1073) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-Separase (Ser1073) Polyclonal Antibody

Anti-Phospho-Separase (Ser1073) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11270

Anti-Phospho-Separase (Ser1073) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Separase (Ser1073)。Anti-Phospho-Separase (Ser1073) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Separase (Ser1073) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Separase (Ser1073). Anti-Phospho-Separase (Ser1073) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic and Nuclear
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids. Each cell must receive one chromatid of every chromosome, during mitosis. Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys cohesin by means of cleavage, allowing the chromatids to separate and divide with the cell. Separase activity is highly regulated. It not only cleaves cohesin at the onset of anaphase but also cleaves itself, promoting downregulation of separase after anaphase. Should a human cell become an aneuploid (one too many or too few chromatids), the embryo most likely will not survive. Should the embryo survive, it will most likely develop severe birth defects or later develop malignant cancers.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human ESPL1 around the phosphorylation site of Ser1073
抗原种属
Human
基因名称
ESPL1
基因ID
9700
蛋白名称
Separin
Uniprot ID
Q14674
功能
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
化学信息
分子量Theoretical: 198 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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