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ST2/IL-1 RL1 Protein, Human, Recombinant

ST2/IL-1 RL1 Protein, Human, Recombinant

产品编号 TMPY-00850
别名: ST2, IL1RL1, ST2L, IL33R, T1, DER4, ST2V, IL‑1 R4, interleukin 1 receptor-like 1, FIT-1

ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.

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ST2/IL-1 RL1 Protein, Human, Recombinant
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 现货
200 μg ¥ 6,530 5日内发货
500 μg ¥ 13,220 5日内发货
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产品目录号及名称: ST2/IL-1 RL1 Protein, Human, Recombinant (TMPY-00850)
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生物活性 Testing in progress
产品描述 ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
种属 Human
表达系统 HEK293 Cells
标签 Tag Free
蛋白编号 Q01638-2
别名 ST2, IL1RL1, ST2L, IL33R, T1, DER4, ST2V, IL‑1 R4, interleukin 1 receptor-like 1, FIT-1
蛋白构建 The secreted isoform of Human IL1RL1 (NP_003847.2) (Met 1-Phe 328) with five amino acids (DDDDK) at the C-terminus was expressed and purified.
蛋白纯度 > 95 % as determined by SDS-PAGE

TargetMol

分子量 35.6 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 100 mM NaCl, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.

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Keywords

ST2/IL-1 RL1 Protein, Human, Recombinant ST2 IL1RL1 FIT 1 ST-2 DER-4 T-1 ST2L IL33R T1 FIT1 DER 4 T 1 DER4 ST2V IL‑1 R4 interleukin 1 receptor-like 1 ST 2 FIT-1 recombinant recombinant-proteins proteins protein

 

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