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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody

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货号 TMAB-01960

别名 VACHT, Solute carrier family 18(vesicular monoamine) member 3, Solute carrier family 18(vesicular acetylcholine) member 3, Solute carrier family 18 member 3, SLC18A3, rVAT, MGC12716

Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Vesicular Acetylcholine Transporter。Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody 可用于 WB。

Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody

Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01960 别名 VACHT, Solute carrier family 18(vesicular monoamine) member 3, Solute carrier family 18(vesicular acetylcholine) member 3, Solute carrier family 18 member 3, SLC18A3, rVAT, MGC12716

Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Vesicular Acetylcholine Transporter。Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody is a Rabbit antibody targeting Vesicular Acetylcholine Transporter. Anti-Vesicular Acetylcholine Transporter Polyclonal Antibody can be used in WB.
别名VACHT, Solute carrier family 18(vesicular monoamine) member 3, Solute carrier family 18(vesicular acetylcholine) member 3, Solute carrier family 18 member 3, SLC18A3, rVAT, MGC12716
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Rabbit)
验证活性
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Rat Cerebrum tissue lysates
Lane 3: Human SH-SY5Y cell lysates
Primary: Anti-Vesicular Acetylcholine Transporter (TMAB-01960) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57 kDa
Observed band size: 60 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
组织特异性Peripheral and central cholinergic nervous systems.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Vesicular Acetylcholine Transporter (VAChT), (~70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate. VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders.
抗原信息
免疫原
KLH conjugated synthetic peptide: human VAT
抗原种属
Human
基因名称
SLC18A3
基因ID
6572
蛋白名称
Vesicular acetylcholine transporter
Uniprot ID
Q16572
研究领域
Molecular Neuropharmacology,Acetylcholine
功能
Involved in acetylcholine transport into synaptic vesicles.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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