Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 10,800 | 20日内发货 | ||
100 μg | ¥ 18,700 | 20日内发货 |
产品描述 | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. |
种属 | Human |
表达系统 | E. coli |
标签 | N-10xHis-SUMO, C-Myc |
蛋白编号 | Q6RW13 |
别名 | ATRAP, AT1 receptor-associated protein, Type-1 angiotensin II receptor-associated protein |
氨基酸序列 | MELPAVNLKVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGGELLVHTGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY |
蛋白构建 | 1-159 aa |
蛋白纯度 | > 85% as determined by SDS-PAGE. |
分子量 | 37.4 kDa (predicted) |
缓冲液 | Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. |
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AGTRAP Protein, Human, Recombinant (His & Myc & SUMO) ATRAP AT1 receptor-associated protein Type-1 angiotensin II receptor-associated protein recombinant recombinant-proteins proteins protein