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Anti-pro Caspase 7 Antibody (8A709)
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产品编号 TMAC-03428
别名 ICE-like apoptotic protease 3, ICE-LAP3, CMH-1, Caspase-7 subunit p11, CASP7_HUMAN, CASP-7, CASP7, Apoptotic protease Mch-3, apoptosis-related cysteine peptidase
Anti-pro Caspase 7 Antibody (8A709) 是一种 Rabbit 抗体，靶向 pro Caspase 7。Anti-pro Caspase 7 Antibody (8A709) 可用于 WB,ICC/IF,IHC。
Anti-pro Caspase 7 Antibody (8A709)
Anti-pro Caspase 7 Antibody (8A709)
还可以产品编号 TMAC-03428 别名 ICE-like apoptotic protease 3, ICE-LAP3, CMH-1, Caspase-7 subunit p11, CASP7_HUMAN, CASP-7, CASP7, Apoptotic protease Mch-3, apoptosis-related cysteine peptidase
Anti-pro Caspase 7 Antibody (8A709) 是一种 Rabbit 抗体，靶向 pro Caspase 7。Anti-pro Caspase 7 Antibody (8A709) 可用于 WB,ICC/IF,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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| 产品描述 | Anti-pro Caspase 7 Antibody (8A709) is a Rabbit antibody targeting pro Caspase 7. Anti-pro Caspase 7 Antibody (8A709) can be used in WB,ICC/IF,IHC. |
| 别名 | ICE-like apoptotic protease 3, ICE-LAP3, CMH-1, Caspase-7 subunit p11, CASP7_HUMAN, CASP-7, CASP7, Apoptotic protease Mch-3, apoptosis-related cysteine peptidase |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of pro Caspase 7 on human lung lysates using anti-pro Caspase 7 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-pro Caspase 7 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-pro Caspase 7 antibody. Counter stained with hematoxylin. 4. ICC staining pro Caspase 7 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining pro Caspase 7 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 34 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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