购物车
- 全部删除
- 您的购物车当前为空
Anti-CD93/C1qR1 Antibody (9Z271) 是一种 Mouse 抗体,靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (9Z271) 可用于 ELISA(Cap)。
Anti-CD93/C1qR1 Antibody (9Z271) 是一种 Mouse 抗体,靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (9Z271) 可用于 ELISA(Cap)。
产品描述 | Anti-CD93/C1qR1 Antibody (9Z271) is a Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody (9Z271) can be used in ELISA(Cap). |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 9Z271 |
交叉反应 | Human |
应用 | ELISA(Cap) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD93/C1qR (rh CD93/C1qR; TMPY-02268; Q9NPY3; Met1-Lys580). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD93/C1qR Protein (TMPY-02268) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容