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Anti-Endostatin Polyclonal Antibody 2

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货号 TMAB-05569

Anti-Endostatin Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Endostatin。Anti-Endostatin Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-Endostatin Polyclonal Antibody 2

Anti-Endostatin Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-05569

Anti-Endostatin Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Endostatin。Anti-Endostatin Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-Endostatin Polyclonal Antibody 2 is a Rabbit antibody targeting Endostatin. Anti-Endostatin Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:400-800; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Present in multiple organs with highest levels in liver, lung and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Two transcript variants encoding different isoforms have been found for this gene.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Endostatin
抗原种属
Human
基因名称
COL18A1
基因ID
蛋白名称
Collagen alpha-1(XVIII) chain
Uniprot ID
功能
COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
化学信息
分子量Theoretical: 190 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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