Name: IgG1 Fc Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPK-00759
Price: 450 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

5 μg

¥ 450

现货

10 μg

¥ 680

现货

20 μg

¥ 1,020

3日内发货

50 μg

¥ 1,740

现货

100 μg

¥ 2,610

现货

200 μg

¥ 3,920

5日内发货

500 μg

¥ 6,670

5日内发货

生物活性

产品描述	IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
生物活性	Human FcRn, His Tag captured on CM5 Chip via anti-his antibody can bind Human IgG1 Fc, No Tag with an affinity constant of 0.28 μM as determined in SPR assay.
研究背景	IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
种属	Human
表达系统	HEK293 Cells
标签	Tag Free
蛋白编号	P01857-1
蛋白构建	Asp104-Lys330
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	VH7183, RGD1359539, Igh-4, IgG1
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	25.5 kDa (predicted). Due to glycosylation, the protein migrates to 31-33 kDa based on Tris-Bis PAGE result.
颜色	White
物理性状	Lyophilized powder

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

IgG1 Fc Protein, Human, Recombinant

IgG1 Fc Protein, Human, Recombinant

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