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Anti-CDK11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CDK11。Anti-CDK11 Polyclonal Antibody 可用于 ICC/IF。
Anti-CDK11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CDK11。Anti-CDK11 Polyclonal Antibody 可用于 ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-CDK11 Polyclonal Antibody is a Rabbit antibody targeting CDK11. Anti-CDK11 Polyclonal Antibody can be used in ICC/IF. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep) |
| 应用 | ICC/IF |
| 推荐剂量 | ICC/IF: 1:50-200 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human CDK11 |
| 抗原种属 | Human |
| 基因名称 | CDK11B |
| 基因ID | |
| 蛋白名称 | Cyclin-dependent kinase 11B |
| 功能 | Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression. |
| 分子量 | Theoretical: 93 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |