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顶部生物活性储存和溶解信息计算器

Anti-SEMA4D Antibody (2P72)

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产品编号 TMAH-01081
别名 Semaphorin-4D, SEMAJ, SEMA4D, M-sema-G, MGC169141, MGC169138, FLJ46484, FLJ39737, FLJ34282, FLJ33485, coll-4, CD100, C9orf164

Anti-SEMA4D Antibody (2P72) 是一种抗体，靶向 SEMA4D。Anti-SEMA4D Antibody (2P72) 可用于 ELISA,FCM。

Anti-SEMA4D Antibody (2P72)

Anti-SEMA4D Antibody (2P72)

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产品编号 TMAH-01081 别名 Semaphorin-4D, SEMAJ, SEMA4D, M-sema-G, MGC169141, MGC169138, FLJ46484, FLJ39737, FLJ34282, FLJ33485, coll-4, CD100, C9orf164

Anti-SEMA4D Antibody (2P72) 是一种抗体，靶向 SEMA4D。Anti-SEMA4D Antibody (2P72) 可用于 ELISA,FCM。

规格价格库存数量
50 μL
¥ 1,310
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-SEMA4D Antibody (2P72) is an antibody targeting SEMA4D. Anti-SEMA4D Antibody (2P72) can be used in ELISA,FCM.
别名Semaphorin-4D, SEMAJ, SEMA4D, M-sema-G, MGC169141, MGC169138, FLJ46484, FLJ39737, FLJ34282, FLJ33485, coll-4, CD100, C9orf164
Ig Type
Human IgG4(S228P)
克隆号
2P72
交叉反应
Human
验证活性
1. Untransfected HEK293T cells surface (green line) and transfected Human SEMA4D HEK293T stable cells surface (red line) were stained with anti-SEMA4D antibody (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
2. The Binding Activity of Mouse Sema4d with Anti-SEMA4D recombinant antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Sema4d at 2 μg/mL can bind Anti-SEMA4D recombinant antibody, the EC50 is 98.14-174.8 ng/mL.
3. The Binding Activity of Human SEMA4D with Anti-SEMA4D recombinant antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SEMA4D at 2 μg/mL can bind Anti-SEMA4D recombinant antibody, the EC50 is 1.082-4.805 ng/mL.
应用ELISAFCM
推荐剂量
FCM:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human SEMA4D Protein
抗原种属
Human
基因名称
SEMA4D
基因ID
10507
Uniprot ID
Q92854
研究领域
Neuroscience, Immunology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

MGC-169141MGC-169138MGC 169141MGC 169138FLJ-46484FLJ-39737FLJ-34282FLJ-33485FLJ 46484FLJ 39737FLJ 34282FLJ 33485CD-100CD 100

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