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Anti-HtrA2/Omi Antibody (8L413)
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产品编号 TMAC-02066
别名 PRSS25, PARK13, OMI, HtrA serine peptidase 2
Anti-HtrA2/Omi Antibody (8L413) 是一种 Rabbit 抗体，靶向 HtrA2/Omi。Anti-HtrA2/Omi Antibody (8L413) 可用于 WB,IHC,IP。
Anti-HtrA2/Omi Antibody (8L413)
Anti-HtrA2/Omi Antibody (8L413)
还可以产品编号 TMAC-02066 别名 PRSS25, PARK13, OMI, HtrA serine peptidase 2
Anti-HtrA2/Omi Antibody (8L413) 是一种 Rabbit 抗体，靶向 HtrA2/Omi。Anti-HtrA2/Omi Antibody (8L413) 可用于 WB,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-HtrA2/Omi Antibody (8L413) is a Rabbit antibody targeting HtrA2/Omi. Anti-HtrA2/Omi Antibody (8L413) can be used in WB,IHC,IP. |
| 别名 | PRSS25, PARK13, OMI, HtrA serine peptidase 2 |
| Ig Type | IgG |
| 克隆号 | 8L413 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of HtrA2 on 293 cell lysates using anti-HtrA2 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-HtrA2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The human homolog of the E. Coli htrA gene product, HtrA, is identified in osteoarthritic cartilage and is repressed in SV40-transformed fibroblast. The gene encoding HtrA protein is highly conserved among mammalian species and belongs to the serine protease family. The HtrA protein contains an IGF-binding domain and exhibits endoproteolytic activity, including autocatalytic cleavage. HtrA is a secreted protein that is expressed in heterologous systems. HtrA plays a role in the degradation of denatured proteins and cell growth regulation. Human HtrA2 (also designated Omi), a novel member of the HtrA serine protease family, is highly homologous to HtrA (also known as L56 and HtrA1). HtrA2 is a ubiquitously expressed nuclear protease that is capable of autoproteolysis. The HtrA2 protein exists as two polypeptides and as an alternatively spliced form called D-Omi, which is predominately expressed in the kidney, colon and thyroid. Due to a modified PDZ domain, D-Omi does not interact with the known partner of HtrA2, the Mxi2 protein. Like HtrA, HtrA2 is involved in the degradation aberrantly folded proteins during conditions of cellular stress, suggesting that it may possess a chaperone-like role under normal conditions. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 38 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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