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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RASAL1 Polyclonal Antibody

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货号 TMAB-12105

Anti-RASAL1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RASAL1。Anti-RASAL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RASAL1 Polyclonal Antibody

Anti-RASAL1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12105

Anti-RASAL1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RASAL1。Anti-RASAL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-RASAL1 Polyclonal Antibody is a Rabbit antibody targeting RASAL1. Anti-RASAL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ras GTPase activating-like protein (RASAL) or RASAL1 is a member of the GAP1 family, and a Ca2+ sensor responding in-phase to repetitive Ca2+ signals by associating with the plasma membrane and deactivating Ras. It contains a conserved domain structure comprising N-terminal tandem C2 domains, a highly conserved central RasGAP domain, and a C-terminal pleckstrin-homology domain that is associated with a Bruton's tyrosine kinase motif. RASAL, like Ca2+ -promoted Ras inactivator (CAPRI, or RASAL4), is a cytosolic protein that undergoes a rapid translocation to the plasma membrane in response to receptor-mediated elevation in the concentration of intracellular free Ca2+, a translocation that activates its ability to function as a RasGAP. However, unlike RASAL4, RASAL undergoes an oscillatory translocation to the plasma membrane that occurs in synchrony with repetitive Ca2+ spikes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RASAL1
抗原种属
Human
基因名称
RASAL1
基因ID
8437
蛋白名称
RasGAP-activating-like protein 1
Uniprot ID
O95294
功能
Probable inhibitory regulator of the Ras-cyclic AMP pathway.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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