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顶部生物活性储存和溶解信息计算器

Anti-CDKN1B Antibody (9B660)

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产品编号 TMAC-02947
别名 p27Kip1, KIP1, Cyclin-Dependent Kinase Inhibitor p27, Cyclin-Dependent Kinase Inhibitor 1B, CDKN1B

Anti-CDKN1B Antibody (9B660) 是一种 Rabbit 抗体，靶向 CDKN1B。Anti-CDKN1B Antibody (9B660) 可用于 FCM,ICC/IF,IHC,IP,WB。

Anti-CDKN1B Antibody (9B660)

Anti-CDKN1B Antibody (9B660)

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Rating icon 还可以
产品编号 TMAC-02947 别名 p27Kip1, KIP1, Cyclin-Dependent Kinase Inhibitor p27, Cyclin-Dependent Kinase Inhibitor 1B, CDKN1B

Anti-CDKN1B Antibody (9B660) 是一种 Rabbit 抗体，靶向 CDKN1B。Anti-CDKN1B Antibody (9B660) 可用于 FCM,ICC/IF,IHC,IP,WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-CDKN1B Antibody (9B660) is a Rabbit antibody targeting CDKN1B. Anti-CDKN1B Antibody (9B660) can be used in FCM,ICC/IF,IHC,IP,WB.
别名p27Kip1, KIP1, Cyclin-Dependent Kinase Inhibitor p27, Cyclin-Dependent Kinase Inhibitor 1B, CDKN1B
Ig Type
IgG
克隆号
9B660
交叉反应
Human,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-p27 KIP 1 antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-p27 KIP 1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-p27 KIP 1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-p27 KIP 1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-p27 KIP 1 antibody. Counter stained with hematoxylin.
6. ICC staining p27 KIP 1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining p27 KIP 1 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. Flow cytometric analysis of Hela cells with p27 KIP 1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
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应用FCMICC/IFIHCIPWB
推荐剂量
WB: 1:1000; IHC: 1:100-500; ICC/IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cell cycle progression is regulated by a series of cyclin-dependent kinases consisting of catalytic subunits, designated Cdks, as well as activating subunits, designated cyclins. Orderly progression through the cell cycle requires the activation and inactivation of different cyclin-Cdks at appropriate times. A series of proteins has recently been described that function as "mitotic inhibitors." These include p21, the levels of which are elevated upon DNA damage in G1 in a p53-dependent manner; p16; and a more recently described p16-related inhibitor designated p15. A p21-related protein, p27, has been described as a negative regulator of G1 progression and speculated to function as a possible mediator of TGFβ-induced G1 arrest. p27 interacts strongly with D-type cyclins and Cdk4 in vitro and, to a lesser extent, with cyclin E and Cdk2.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P46527
化学信息
分子量Theoretical: 27 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

KIP-1KIP 1

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