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Anti-IL-22RA2 Antibody (4D840) 是一种 Rabbit 抗体,靶向 IL-22RA2。Anti-IL-22RA2 Antibody (4D840) 可用于 ELISA。
Anti-IL-22RA2 Antibody (4D840) 是一种 Rabbit 抗体,靶向 IL-22RA2。Anti-IL-22RA2 Antibody (4D840) 可用于 ELISA。
产品描述 | Anti-IL-22RA2 Antibody (4D840) is a Rabbit antibody targeting IL-22RA2. Anti-IL-22RA2 Antibody (4D840) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4D840 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL22RA2 / IL22BP (rh IL22BP; TMPY-01220; NP_851826.1; Met 1-Pro 231). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and contains 3 fibronectin type-III domains. IL-22BP/IL-22RA2 is expressed in a range of tissues, including those in the digestive, female reproductive, and immune systems. It is expressed in the placenta, spleen, breast, skin, and lung. It is also detected in the intestinal tract, testis, brain, heart, and thymus. The dominant cell types expressing IL-22BP/IL-22RA2 were mononuclear cells and epithelium. IL-22BP/IL-22RA2 may play an important role as an IL-22 antagonist in the regulation of inflammatory responses. Interleukin-22 (IL-22) is a member of the IL-10 family. It is produced by T cells and induces the production of acute-phase reactants. IL-22 plays important role in the immune response through activation of the STAT 3 signal transduction pathway. Two types of IL-22-binding receptors have been discovered, a membrane-bound receptor and a soluble receptor. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IL22BP protein (TMPY-01220) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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