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Anti-REG1B Antibody (6U932)

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产品编号 TMAY-01951

Anti-REG1B Antibody (6U932) 是一种 Rabbit 抗体,靶向 REG1B。Anti-REG1B Antibody (6U932) 可用于 IHC-P。

Anti-REG1B Antibody (6U932)

Anti-REG1B Antibody (6U932)

Rating icon 还可以
产品编号 TMAY-01951

Anti-REG1B Antibody (6U932) 是一种 Rabbit 抗体,靶向 REG1B。Anti-REG1B Antibody (6U932) 可用于 IHC-P。

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产品介绍

生物活性
产品描述
Anti-REG1B Antibody (6U932) is a Rabbit antibody targeting REG1B. Anti-REG1B Antibody (6U932) can be used in IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
6U932
交叉反应
Human
验证活性
Immunochemical staining of human REG1B in human pancreas with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用
IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human REG1B (rh REG1B; TMPY-01394; NP_006498.1; Met1-Asn166).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells, and could be associated with fibrocalculous pancreatopathy. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family consisting of four subtypes (types I, II, III, IV) and are involved in cancers and neurodegenerative diseases. Regenerating islet-derived 1 beta (REG1B), also known as Lithostathine-1-beta and Pancreatic stone protein 2 (PSPS2), is a types I Reg protein and contains one typical C-type lectin domain. REG1B is a 166-amino acid protein that has 22 amino acid substitutions in comparison with the previously isolated human REG1A, and it is was expressed only in pancreas. REG1B Is normally found in the exocrine pancreas, whereas in other tissues it appears either only under pathological conditions, such as Alzheimer's disease (brain), cancer (colon), or during regeneration such as neuronal sprouting in brain and pancreas regeneration. REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. The REG1A and REG1B gene and proteins could play different roles in the pancreas.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human REG1B protein (TMPY-01394)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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4个月前
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