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别名 RO7030816, RO 7187797, RG 7828, RG 6160, Mosunetuzumab-axgb, Lunsumio, Cevostamab, BTCT-4465A, BFCR 4350A, Anti-FCRH5/CD3 BiTE
Anti-Mosunetuzumab Antibody (9L411) 是一种 Rabbit 抗体,靶向 Mosunetuzumab。Anti-Mosunetuzumab Antibody (9L411) 可用于 ELISA, Sandwich ELISA, Competitive ELISA。
Anti-Mosunetuzumab Antibody (9L411) 是一种 Rabbit 抗体,靶向 Mosunetuzumab。Anti-Mosunetuzumab Antibody (9L411) 可用于 ELISA, Sandwich ELISA, Competitive ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 40 μg | ¥ 3,218 | 5日内发货 |
| 产品描述 | Anti-Mosunetuzumab Antibody (9L411) is a Rabbit antibody targeting Mosunetuzumab. Anti-Mosunetuzumab Antibody (9L411) can be used in ELISA, Sandwich ELISA, Competitive ELISA. |
| 别名 | RO7030816, RO 7187797, RG 7828, RG 6160, Mosunetuzumab-axgb, Lunsumio, Cevostamab, BTCT-4465A, BFCR 4350A, Anti-FCRH5/CD3 BiTE |
| Ig Type | IgG, κ |
| 克隆号 | 9L411 |
| 特异性 | Mosunetuzumab and Cevostamab |
| 应用 | ELISASandwich ELISACompetitive ELISA |
| 推荐剂量 | ELISA: 0.01-1 µg/ml; Sandwich ELISA: 0.4-2 μg/ml; Competitive ELISA: 1-10 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 纯化方式 | Protein A affinity column |
| 性状 | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| 缓冲液 | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| 研究背景 | Mosunetuzumab is an innovative bispecific antibody that has a structure that resembles a natural human antibody, with two 'Fab' regions. However, it differs from naturally-occurring antibodies as one 'Fab' region targets CD20 and the other targets CD3. By recognizing and binding to these two different targets, Mosunetuzumab is able to redirect the cytotoxic activity of T-cells towards cancerous B-cells. This unique mechanism of action holds great potential for enhancing the effectiveness of cancer treatment. Cevostamab (BFCR4350A) is an innovative bispecific antibody, designed to engage T-cells and myeloma cells by targeting FcRH5 and CD3 receptors, respectively. Cevostamab possesses a unique structure with two 'Fab' regions, with one specifically targeting FcRH5 and the other targeting CD3. This dual targeting mechanism activates the patient's own T-cells and redirects them to eliminate myeloma cells expressing FcRH5 by releasing cytotoxic proteins. |
| 偶联 | Unconjugated |
| 免疫原 | Mosunetuzumab |
| 储存方式 | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |