Anti-APP Antibody (3L659)

Name: Anti-APP Antibody (3L659)
Brand: TargetMol
SKU: TMAH-00073
Rating: 4.5 (1 reviews)

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产品编号 TMAH-00073

别名 APP695, Amyloid Precursor Protein 695, Amyloid Precursor

Anti-APP Antibody (3L659) 是一种 Mouse 抗体，靶向 APP。Anti-APP Antibody (3L659) 可用于 ELISA, WB, IHC, IF。

Anti-APP Antibody (3L659)

还可以

产品编号 TMAH-00073 别名 APP695, Amyloid Precursor Protein 695, Amyloid Precursor

Anti-APP Antibody (3L659) 是一种 Mouse 抗体，靶向 APP。Anti-APP Antibody (3L659) 可用于 ELISA, WB, IHC, IF。

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产品描述	Anti-APP Antibody (3L659) is a Mouse antibody targeting APP. Anti-APP Antibody (3L659) can be used in ELISA, WB, IHC, IF.
别名	APP695, Amyloid Precursor Protein 695, Amyloid Precursor
Ig Type	IgG2b
克隆号	3L659
交叉反应	Human, Mouse
验证活性	1. Western blot -All lanes: Amyloid beta A4 antibody at 1µg/ml -Lane 1: Mouse heart tissue -Lane 2: Mouse kidney tissue -Lane 3: Mouse lung tissue -Secondary: Goat polyclonal to Mouse IgG at 1/15000 dilution -Predicted band size: 30, 35, 72, 80 kDa -Observed band size: 30, 35, 72 kDa 2. Immunohistochemistry of paraffin-embedded human brain tissue using TMAH-00073 at dilution of 1:200 3. Immunofluorescent analysis of Hela cells using TMAH-00073 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) 4. Immunofluorescent analysis of HepG2 cells using TMAH-00073 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
应用	ELISA, WB, IHC, IF
抗体种类	Monoclonal
宿主来源	Mouse
亚细胞定位	Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, growth cone. Membrane, clathrin-coated pit. Early endosome. Cytoplasmic vesicle.; [C83]: Endoplasmic reticulum. Golgi apparatus. Early endosome.; [C99]: Early endosome.; [Soluble APP-beta]: Secreted.; [Amyloid-beta protein 42]: Cell surface.; [Gamma-secretase C-terminal fragment 59]: Nucleus. Cytoplasm.
构建方式	Hybridoma Monoclonal Antibody
纯化方式	Protein G purified
性状	Liquid
缓冲液	Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
纯度	>95%
研究背景	Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as...