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Anti-EDA2R Antibody (1P827)
还可以产品编号 TMAY-02093
别名 ectodysplasin A2 receptor
Anti-EDA2R Antibody (1P827) 是一种 Rabbit 抗体，靶向 EDA2R。Anti-EDA2R Antibody (1P827) 可用于 ELISA。
Anti-EDA2R Antibody (1P827)
Anti-EDA2R Antibody (1P827)
还可以产品编号 TMAY-02093 别名 ectodysplasin A2 receptor
Anti-EDA2R Antibody (1P827) 是一种 Rabbit 抗体，靶向 EDA2R。Anti-EDA2R Antibody (1P827) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,294 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-EDA2R Antibody (1P827) is a Rabbit antibody targeting EDA2R. Anti-EDA2R Antibody (1P827) can be used in ELISA. |
| 别名 | ectodysplasin A2 receptor |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1P827 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human XEDAR / EDA2R (rh XEDAR / EDA2R; TMPY-01932; NP_068555.1; Met1-Thr138). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2, but not for EDA isoform A1. TNFRSF27 / EDA2R mediates the activation of the NF-kappa-B and JNK pathways. The activation seems to be mediated by binding to TRAF3 and TRAF6. Ectodysplasin, a member of the tumor necrosis factor family, is encoded by the anhidrotic ectodermal dysplasia EDA gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that differ only by an insertion of two amino acids. This insertion functions to determine receptor binding specificity, such that EDA-A1 binds only the receptor EDAR, whereas EDA-A2 binds only the related, but distinct, X-linked ectodysplasin-A2 receptor (XEDAR). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human XEDAR / EDA2R protein (TMPY-01932) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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