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Anti-Olig-2/Oligo2 Antibody (2L225)

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Anti-Olig-2/Oligo2 Antibody (2L225)
产品编号 TMAC-02918
别名 RACK17, PRKCBP2, OLIGO2, Olig2, bHLHe19, BHLHB1

Anti-Olig-2/Oligo2 Antibody (2L225) 是一种 Rabbit 抗体,靶向 Olig-2/Oligo2。Anti-Olig-2/Oligo2 Antibody (2L225) 可用于 WB,IHC,ICC/IF。

Anti-Olig-2/Oligo2 Antibody (2L225)

Anti-Olig-2/Oligo2 Antibody (2L225)

Rating icon 还可以
Anti-Olig-2/Oligo2 Antibody (2L225)
产品编号 TMAC-02918 别名 RACK17, PRKCBP2, OLIGO2, Olig2, bHLHe19, BHLHB1

Anti-Olig-2/Oligo2 Antibody (2L225) 是一种 Rabbit 抗体,靶向 Olig-2/Oligo2。Anti-Olig-2/Oligo2 Antibody (2L225) 可用于 WB,IHC,ICC/IF。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Olig-2/Oligo2 Antibody (2L225) is a Rabbit antibody targeting Olig-2/Oligo2. Anti-Olig-2/Oligo2 Antibody (2L225) can be used in WB,IHC,ICC/IF.
别名RACK17, PRKCBP2, OLIGO2, Olig2, bHLHe19, BHLHB1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Olig2 antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Olig2 antibody. Counter stained with hematoxylin.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 32 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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