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SLAMF6 Protein, Human, Recombinant (His)

SLAMF6 Protein, Human, Recombinant (His)

产品编号 TMPY-01914
别名: SLAM family member 6, CD352, KALI, SF2000, NTB-A, Ly108, NTBA, KALIb

SLAMF6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.3 kDa and the accession number is Q96DU3-1.

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SLAMF6 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 5日内发货
1 mg ¥ 24,900 5日内发货
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产品目录号及名称: SLAMF6 Protein, Human, Recombinant (His) (TMPY-01914)
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生物活性
技术参数
产品性质
参考文献
生物活性 Measured by its ability to bind biotinylated recombinant human SH2D1A in a functional ELISA.
产品描述 SLAMF6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.3 kDa and the accession number is Q96DU3-1.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 Q96DU3-1
别名 SLAM family member 6, CD352, KALI, SF2000, NTB-A, Ly108, NTBA, KALIb
蛋白构建 The Human SLAMF6 (Q96DU3-1) extracellular domain (Met 1-Met 226) was expressed, with a polyhistidine tag at the C-terminus.
蛋白纯度 > 90 % as determined by SDS-PAGE
分子量 24.3 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.

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Keywords

SLAMF6 Protein, Human, Recombinant (His) SLAM family member 6 SF-2000 CD352 CD-352 KALI SF2000 NTB-A Ly108 CD 352 NTBA KALIb SF 2000 recombinant recombinant-proteins proteins protein

 

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