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Anti-Tuberin Antibody (9I375) 是一种 Rabbit 抗体,靶向 Tuberin。Anti-Tuberin Antibody (9I375) 可用于 WB,IHC,FCM。
Anti-Tuberin Antibody (9I375) 是一种 Rabbit 抗体,靶向 Tuberin。Anti-Tuberin Antibody (9I375) 可用于 WB,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-Tuberin Antibody (9I375) is a Rabbit antibody targeting Tuberin. Anti-Tuberin Antibody (9I375) can be used in WB,IHC,FCM. |
别名 | Tuberous sclerosis 2 protein homolog, Tuberous sclerosis 2 protein, Tuberous sclerosis 2, Tuberin, TSC4, formerly, TSC4 gene, formerly, TSC4, TSC2_HUMAN, tsc2, Protein phosphatase 1, regulatory subunit 160, PPP1R160, OTTHUMP00000198395, OTTHUMP00000198394, OTTHUMP00000158940, LAM, FLJ43106 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of Tuberin on Jurkat cell lysates using anti-Tuberin antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Tuberin antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of Hela cells with Tuberin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 200 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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