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别名 Ly-60, intercellular adhesion molecule 2, Icam-2, CD102
Anti-ICAM-2/CD102 Antibody (2O9) 是一种 Rabbit 抗体,靶向 ICAM-2/CD102。Anti-ICAM-2/CD102 Antibody (2O9) 可用于 WB。
Anti-ICAM-2/CD102 Antibody (2O9) 是一种 Rabbit 抗体,靶向 ICAM-2/CD102。Anti-ICAM-2/CD102 Antibody (2O9) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,284 | 5日内发货 |
| 产品描述 | Anti-ICAM-2/CD102 Antibody (2O9) is a Rabbit antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (2O9) can be used in WB. |
| 别名 | Ly-60, intercellular adhesion molecule 2, Icam-2, CD102 |
| Ig Type | Rabbit IgG |
| 克隆号 | 2O9 |
| 交叉反应 | Human |
| 特异性 | Human ICAM-2/CD102 |
| 验证活性 | Anti-ICAM2 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Hela S3 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:31 kDa. -Observed band size:31 kDa(We are unsure as to the identity of these extra bands.) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; TMPY-01418; NP_000864.2; Met1-Gln223). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human ICAM-2 / CD102 protein (TMPY-01418) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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