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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-S100A8 Antibody-FITC (7D796)

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货号 TMAY-01676F

别名 S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag

Anti-S100A8 Antibody-FITC (7D796) 是一种 FITC-conjugated Mouse 抗体，靶向 S100A8。Anti-S100A8 Antibody-FITC (7D796) 可用于 FCM。

Anti-S100A8 Antibody-FITC (7D796)

Anti-S100A8 Antibody-FITC (7D796)

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Rating icon 还可以
货号 TMAY-01676F 别名 S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag

Anti-S100A8 Antibody-FITC (7D796) 是一种 FITC-conjugated Mouse 抗体，靶向 S100A8。Anti-S100A8 Antibody-FITC (7D796) 可用于 FCM。

规格价格库存数量
25 T
¥ 895
5日内发货
100 T
¥ 1,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-S100A8 Antibody-FITC (7D796) is a FITC-conjugated Mouse antibody targeting S100A8. Anti-S100A8 Antibody-FITC (7D796) can be used in FCM.
别名S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag
Ig Type
Mouse IgG1
克隆号
7D796
反应种属
Human
特异性
Human S100A8
验证活性
Flow cytometric analysis of Human S100A8 expression on human whole blood Granulocytes. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with FITC-conjugated anti-Human S100A8. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable Granulocytes.
应用FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human S100A8 (rh S100A8; TMPY-01356; NP_002955.2; Met1-Glu93) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of S100A8 protein is associated with various diseases and cancers. S100A8 may have an immunoregulatory role by contributing to the regulation of fetal-maternal interactions. It may play a protective role and its absence may allow infiltration by maternal cells, a process eventually manifesting as resorption. The heterodimeric S100 protein complex S100A8/A9 which has been shown to be involved in inflammatory and neoplastic disorders. The complex can induce cell proliferation, or apoptosis, inflammation, collagen synthesis, and cell migration. S100A8/A9 has emerged as important pro-inflammatory mediator in acute and chronic inflammation. More recently, increased S100A8 and S100A9 levels were also detected in various human cancers, presenting abundant expression in neoplastic tumor cells as well as infiltrating immune cells. On the one hand, S100A8/A9 is a powerful apoptotic agent produced by immune cells, making it a very fascinating tool in the battle against cancer. It spears the risk to induce auto-immune response and may serve as a lead compound for cancer-selective therapeutics. In contrast, S100A8/A9 expression in cancer cells has also been associated with tumor development, cancer invasion or metastasis. Altogether, its expression and potential cytokine-like function in inflammation and cancer suggest that S100A8/A9 may play a key role in inflammation-associated cancer.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human S100A8 Protein (TMPY-01356)
抗原种属
Human
研究领域
Calcium-binding Proteins and Related Molecules
储存&溶解度
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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