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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HSD17B1 Polyclonal Antibody

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货号 TMAB-07315

Anti-HSD17B1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HSD17B1。Anti-HSD17B1 Polyclonal Antibody 可用于 WB。

Anti-HSD17B1 Polyclonal Antibody

Anti-HSD17B1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07315

Anti-HSD17B1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HSD17B1。Anti-HSD17B1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-HSD17B1 Polyclonal Antibody is a Rabbit antibody targeting HSD17B1. Anti-HSD17B1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
抗原信息
免疫原
KLH conjugated synthetic peptide: human HSD17B1
抗原种属
Human
基因名称
HSD17B1
基因ID
3292
蛋白名称
17-beta-hydroxysteroid dehydrogenase type 1
Uniprot ID
P14061
功能
Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
化学信息
分子量Theoretical: 35 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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