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Anti-SNAP-25 Antibody (5K558)
还可以产品编号 TMAY-01916
Anti-SNAP-25 Antibody (5K558) 是一种 Rabbit 抗体，靶向 SNAP-25。Anti-SNAP-25 Antibody (5K558) 可用于 ELISA。
Anti-SNAP-25 Antibody (5K558)
Anti-SNAP-25 Antibody (5K558)
还可以产品编号 TMAY-01916
Anti-SNAP-25 Antibody (5K558) 是一种 Rabbit 抗体，靶向 SNAP-25。Anti-SNAP-25 Antibody (5K558) 可用于 ELISA。
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抗原信息
| 产品描述 | Anti-SNAP-25 Antibody (5K558) is a Rabbit antibody targeting SNAP-25. Anti-SNAP-25 Antibody (5K558) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5K558 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human SNAP25 (rh SNAP25; TMPY-02245; P60880-1; Met1-Gly206). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. SNAP25 / SUP is a Q-SNARE protein contributing two α-helices in the formation of the exocytotic fusion complex in neurons where it assembles with syntaxin-1 and synaptobrevin. SNAP25 / SUP is involved in the molecular regulation of neurotransmitter release. It may play an important role in the synaptic function of specific neuronal systems. SNAP25 / SUP associates with proteins involved in vesicle docking and membrane fusion. SNAP25 / SUP regulates plasma membrane recycling through its interaction with CENPF. SNAP25 / SUP inhibits P/Q- and L-type voltage-gated calcium channels located presynaptically and interacts with the synaptotagmin C2B domain in Ca2+-independent fashion. In glutamatergic synapses SNAP25 / SUP decreases the Ca2+ responsiveness, while it is naturally absent in GABAergic synapses. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human SNAP25 protein (TMPY-02245) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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