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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CHRNB3 Polyclonal Antibody

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货号 TMAB-04335

Anti-CHRNB3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CHRNB3。Anti-CHRNB3 Polyclonal Antibody 可用于 WB。

Anti-CHRNB3 Polyclonal Antibody

Anti-CHRNB3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04335

Anti-CHRNB3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CHRNB3。Anti-CHRNB3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CHRNB3 Polyclonal Antibody is a Rabbit antibody targeting CHRNB3. Anti-CHRNB3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region.[supplied by OMIM, Apr 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CHRNB3
抗原种属
Human
基因名称
CHRNB3
基因ID
1142
蛋白名称
Neuronal acetylcholine receptor subunit beta-3
Uniprot ID
Q05901
功能
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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