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Anti-GPA33/A33 Antibody (2X371)
还可以产品编号 TMAY-01819
别名 MGC129987, MGC129986, GPA33, Glycoprotein A33, A33
Anti-GPA33/A33 Antibody (2X371) 是一种 Rabbit 抗体，靶向 GPA33/A33。Anti-GPA33/A33 Antibody (2X371) 可用于 ELISA,IHC-P。
Anti-GPA33/A33 Antibody (2X371)
Anti-GPA33/A33 Antibody (2X371)
还可以产品编号 TMAY-01819 别名 MGC129987, MGC129986, GPA33, Glycoprotein A33, A33
Anti-GPA33/A33 Antibody (2X371) 是一种 Rabbit 抗体，靶向 GPA33/A33。Anti-GPA33/A33 Antibody (2X371) 可用于 ELISA,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 790 | 5日内发货 | |
| 100 μL | ¥ 2,294 | 5日内发货 |
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抗原信息
| 产品描述 | Anti-GPA33/A33 Antibody (2X371) is a Rabbit antibody targeting GPA33/A33. Anti-GPA33/A33 Antibody (2X371) can be used in ELISA,IHC-P. |
| 别名 | MGC129987, MGC129986, GPA33, Glycoprotein A33, A33 |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2X371 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human GPA33 in human small intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium. 2. Immunochemical staining of human GPA33 in human colon with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium. 3. Immunochemical staining of human GPA33 in human colon carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium. |
| 应用 | ELISA,IHC-P |
| 推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human GPA33 (rh GPA33; TMPY-02012; Q99795-1; Met1-Val235). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cell surface A33 antigen, also known as glycoprotein A33, is a single-pass type I membrane protein that is expressed in the normal gastrointestinal epithelium and 95% of colon cancers. GPA33 contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. Intracellular traffic and recycling to the cell surface appear to play a major role in GPA33 function and to have an influence on its surface density superseding translational regulation. GPA33 has become a promising target of immunologic therapy strategies, but its biologic function and potential role in tumorigenesis are unknown. EpCAM protein and GPA33 mRNA expressions are specific and sensitive markers of Barrett's metaplasia (BM). GPA33 may also play a role in cell-cell recognition and signaling.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human GPA33 protein (TMPY-02012) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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