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VB1-050是一种特异性结合GLUT8的全人源单克隆抗体,在实验研究中作为抑制己糖转运、介导细胞毒性载荷递送及研究肿瘤代谢重编程机制的药理学工具。
VB1-050是一种特异性结合GLUT8的全人源单克隆抗体,在实验研究中作为抑制己糖转运、介导细胞毒性载荷递送及研究肿瘤代谢重编程机制的药理学工具。


TargetMol的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
| 产品描述 | VB1-050 is a highly specialized fully human monoclonal antibody target the human solute carrier family 2 member 8 protein, also known as glucose transporter 8 or GLUT8, inhibition of hexose transport and receptor-mediated internalization across various preclinical experimental models of breast, liver, prostate, and colon cancers where the target antigen exhibits preferential expression compared to limited reactivity in normal tissues. |
| 体外活性 | 在结合实验和免疫组化筛选中,VB1-050 在多种人癌细胞系和原发肿瘤组织中展示了对葡萄糖转运蛋白-8 (Glut-8) 的高特异性 [1]。 |
| 反应种属 | Human |
| 应用 | ELISAFACSFunctional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG1 |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | SLC2A8 |
| 存储 | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
对于不同动物的给药剂量换算,您也可以参考 更多