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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-RhoA Antibody (4W246)

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货号 TMAY-02350

别名 RHOH12, RHO12, ras homolog family member A, ARHA, ARH12

Anti-RhoA Antibody (4W246) 是一种 Rabbit 抗体，靶向 RhoA。Anti-RhoA Antibody (4W246) 可用于 FCM。

Anti-RhoA Antibody (4W246)

Anti-RhoA Antibody (4W246)

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Rating icon 还可以
货号 TMAY-02350 别名 RHOH12, RHO12, ras homolog family member A, ARHA, ARH12

Anti-RhoA Antibody (4W246) 是一种 Rabbit 抗体，靶向 RhoA。Anti-RhoA Antibody (4W246) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-RhoA Antibody (4W246) is a Rabbit antibody targeting RhoA. Anti-RhoA Antibody (4W246) can be used in FCM.
别名RHOH12, RHO12, ras homolog family member A, ARHA, ARH12
Ig Type
Rabbit IgG
克隆号
4W246
反应种属
Human
特异性
Human RhoA
验证活性
Flow cytometric analysis of Human RHOA expression on HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human RHOA, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human RhoA (rh RhoA; TMPY-01958; P61586-1; Met1-Leu193).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho family of small GTPases plays a key role in the dynamic regulation of the actin cytoskeleton that underlies various important cellular functions such as shape changes, migration, and polarity. RHOA / ARH12 is part of a larger family of related proteins known as the Ras superfamily; proteins involved in the regulation and timing of cell division. RHOA / ARH12 is a small GTPase protein known to regulate the actin cytoskeleton in the formation of stress fibers. It acts upon two known effector proteins: ROCK1 (Rho-associated, coiled-coil containing protein kinase 1) and DIAPH1 ( diaphanous homolog 1 (Drosophila) ). RHOA / ARH12 regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. RHOA / ARH12 serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. RHOA / ARH12 may be an activator of PLCE1. It is activated by ARHGEF2, which promotes the exchange of GDP for GTP.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Human RhoA Protein (TMPY-01958)
抗原种属
Human
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

RHOH-12RHOH 12RHO-12RHO 12ARH-12ARH 12
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