规格

价格

库存

数量

10 μg

¥ 1,170

6-8日内发货

50 μg

¥ 3,470

5日内发货

500 μg

¥ 12,100

5日内发货

1 mg

待询

5日内发货

生物活性

产品描述	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
生物活性	Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 5-20 ng/ml. (QC verified)
研究背景	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	P01127
氨基酸序列	Ser82-Thr190
蛋白构建	Ser82-Thr190
蛋白纯度	Greater than 98% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
缓冲液	Lyophilized from a 0.2 μm filtered solution of 20 mM NaAC-HAC,4% Mannitol, pH 4.5.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	血小板源生长因子, PDGF-BB, PDGFBB
内毒素	< 0.02 ng/µg (0.2 EU/µg) as determined by LAL test.

化学信息

分子量	14 KDa (reducing condition)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

PDGF-BB Protein, Human, Recombinant

PDGF-BB Protein, Human, Recombinant

产品介绍

引用文献

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