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PDGF-BB Protein, Human, Recombinant

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货号 TMPJ-00735

别名 血小板源生长因子, PDGF-BB, PDGFBB

Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

PDGF-BB Protein, Human, Recombinant
其他形式的 “PDGF-BB Protein, Human, Recombinant”:
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PDGF-BB Protein, Human, Recombinant

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货号 TMPJ-00735 别名 血小板源生长因子, PDGF-BB, PDGFBB

Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

规格价格库存数量
5 μg
¥ 693
现货
10 μg
¥ 1,170
现货
20 μg
¥ 1,860
现货
50 μg
¥ 3,470
3日内发货
100 μg
¥ 4,930
现货
200 μg
¥ 7,350
5日内发货
500 μg
¥ 12,100
5日内发货
1 mg
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5日内发货
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纯度: SDS-PAGE: 98.3%; SEC-HPLC: >99.9%
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产品介绍


生物活性
产品描述
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
生物活性
Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 5-20 ng/ml. (QC verified)
PDGF-BB Protein, Human, Recombinant
研究背景
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
种属
Human
表达系统
E. coli
标签Tag Free
蛋白编号P01127
氨基酸序列Ser82-Thr190
蛋白构建Ser82-Thr190
蛋白纯度
Greater than 98% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
PDGF-BB Protein, Human, RecombinantPDGF-BB Protein, Human, Recombinant
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM NaAc-HAc, pH 4.5.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名血小板源生长因子, PDGF-BB, PDGFBB
内毒素< 0.02 ng/µg (0.2 EU/µg) as determined by LAL test.
化学信息
分子量14 KDa (reducing condition)
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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