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Anti-IL-1 beta Antibody (1F906)
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产品编号 TMAB-00935
Anti-IL-1 beta Antibody (1F906) 是一种 Rabbit 抗体，靶向 IL-1 beta。Anti-IL-1 beta Antibody (1F906) 可用于 WB。
Anti-IL-1 beta Antibody (1F906)
Anti-IL-1 beta Antibody (1F906)
还可以产品编号 TMAB-00935
Anti-IL-1 beta Antibody (1F906) 是一种 Rabbit 抗体，靶向 IL-1 beta。Anti-IL-1 beta Antibody (1F906) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-IL-1 beta Antibody (1F906) is a Rabbit antibody targeting IL-1 beta. Anti-IL-1 beta Antibody (1F906) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 1F906 |
| 交叉反应 | Human |
| 验证活性 | THP-1 (H) cells were treated with or without TPA (80nM) for 24h,then treated with (100ng/ml) lipopolysaccharide (LPS) for 6h, then with (300ng/ml) Brefeldin A added after 3h,25 μg total protein per Lane of cell lysates probed with IL-1 beta monoclonal antibody, unconjugated (TMAB-00935) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 0.05% BSA, 40% Glycerol, 0.02% Proclin300. |
| 研究背景 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]. |
| 免疫原 | A synthesized peptide: human IL 1 beta |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Inflammatory mediators,Interleukins,Obesity,SARS Coronavirus |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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