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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD137 Polyclonal Antibody 2

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货号 TMAB-03844

Anti-CD137 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CD137。Anti-CD137 Polyclonal Antibody 2 可用于 WB。

Anti-CD137 Polyclonal Antibody 2

Anti-CD137 Polyclonal Antibody 2

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货号 TMAB-03844

Anti-CD137 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CD137。Anti-CD137 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-CD137 Polyclonal Antibody 2 is a Rabbit antibody targeting CD137. Anti-CD137 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Expressed on the surface of activated T-cells.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CD137 exists on the cell surface as a monomer with a molecular mass of 30 kDa and as a dimer of 55 kDa. Human and mouse CD137 share 60% amino acid identity. CD137 (4-1BB), a member of the tumour necrosis factor receptor superfamily, is a type I transmembrane glycoprotein expressed on the cell surface of activated splenic T cells and thymocytes. The functions of CD137 in T lymphocytes include regulating activation, proliferation and apoptosis. CD137 and CD28 are costimulatory molecules of T cell activation. Costimulatory molecules are important in initiating anti-tumor immune responses. CD137 plays an important role in regulating T-cell-dependent immune responses. Expression of CD137 correlates negatively with lymphocyte proliferation and positively with the degree of activation-induced cell death caused by mitogen overstimulation. In monocytes, CD137 induces activation, promotes adherence and prolongs survival.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD137
抗原种属
Human
基因名称
TNFRSF9
基因ID
3604
蛋白名称
Tumor necrosis factor receptor superfamily member 9
Uniprot ID
Q07011
功能
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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