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Anti-IL-28B Antibody (2R608)

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Anti-IL-28B Antibody (2R608)
产品编号 TMAY-02137
别名 interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B

Anti-IL-28B Antibody (2R608) 是一种 Rabbit 抗体，靶向 IL-28B。Anti-IL-28B Antibody (2R608) 可用于 ELISA。

Anti-IL-28B Antibody (2R608)
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Anti-IL-28B Antibody (2R608)

Rating icon 还可以
Anti-IL-28B Antibody (2R608)
产品编号 TMAY-02137 别名 interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B

Anti-IL-28B Antibody (2R608) 是一种 Rabbit 抗体，靶向 IL-28B。Anti-IL-28B Antibody (2R608) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-28B Antibody (2R608) is a Rabbit antibody targeting IL-28B. Anti-IL-28B Antibody (2R608) can be used in ELISA.
别名interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B
Ig Type
Rabbit IgG
克隆号
2R608
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-28B / IFN-lambda-3 (rh IL-28B / IFN-lambda-3; TMPY-01872; NP_742151.2; Met1-Val196).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin-28B (IL-28B) also known as Interferon lambda-3 and IFN-lambda-3, belongs to the type III interferon family of cytokines and are highly similar to IL-29. IL-28B belongs to the newly described interferon lambda (IFNλ) family of cytokines. IL-28B is a cytokine with immunomodulatory activity. It functions in Up-regulating MHC class I antigen expression. IL-28B displays potent antiviral activity and antitumor activity. This cytokine serves as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-28B, like IL-12, is capable of robustly enhancing adaptive immunity. Moreover, we describe for the first time how IL-28B reduces regulatory T-cell populations during DNA vaccination, whereas IL-12 increases this cellular subset. We also show that IL-28B, unlike IL-12, can increase the percentage of splenic CD8+ T cells in vaccinated animals and that these cells are more granular and have higher antigen-specific cytolytic degranulation compared with cells taken from animals that received IL-12 as an adjuvant.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human IL-28B / IFN-lambda-3 protein (TMPY-01872)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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