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Anti-IL-28B Antibody (2R608)
还可以产品编号 TMAY-02137
Anti-IL-28B Antibody (2R608) 是一种 Rabbit 抗体，靶向 IL-28B。Anti-IL-28B Antibody (2R608) 可用于 ELISA。
Anti-IL-28B Antibody (2R608)
Anti-IL-28B Antibody (2R608)
还可以产品编号 TMAY-02137
Anti-IL-28B Antibody (2R608) 是一种 Rabbit 抗体，靶向 IL-28B。Anti-IL-28B Antibody (2R608) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-28B Antibody (2R608) is a Rabbit antibody targeting IL-28B. Anti-IL-28B Antibody (2R608) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2R608 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-28B / IFN-lambda-3 (rh IL-28B / IFN-lambda-3; TMPY-01872; NP_742151.2; Met1-Val196). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-28B (IL-28B) also known as Interferon lambda-3 and IFN-lambda-3, belongs to the type III interferon family of cytokines and are highly similar to IL-29. IL-28B belongs to the newly described interferon lambda (IFNλ) family of cytokines. IL-28B is a cytokine with immunomodulatory activity. It functions in Up-regulating MHC class I antigen expression. IL-28B displays potent antiviral activity and antitumor activity. This cytokine serves as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-28B, like IL-12, is capable of robustly enhancing adaptive immunity. Moreover, we describe for the first time how IL-28B reduces regulatory T-cell populations during DNA vaccination, whereas IL-12 increases this cellular subset. We also show that IL-28B, unlike IL-12, can increase the percentage of splenic CD8+ T cells in vaccinated animals and that these cells are more granular and have higher antigen-specific cytolytic degranulation compared with cells taken from animals that received IL-12 as an adjuvant. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL-28B / IFN-lambda-3 protein (TMPY-01872) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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