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Anti-IL12RB2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL12RB2。Anti-IL12RB2 Polyclonal Antibody 可用于 WB,ELISA。
Anti-IL12RB2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL12RB2。Anti-IL12RB2 Polyclonal Antibody 可用于 WB,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 |
| 产品描述 | Anti-IL12RB2 Polyclonal Antibody is a Rabbit antibody targeting IL12RB2. Anti-IL12RB2 Polyclonal Antibody can be used in WB,ELISA. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse) |
| 应用 | WBELISA |
| 推荐剂量 | WB: 1:500-2000; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single pass type I membrane protein. |
| 组织特异性 | Isoform 2 is expressed at similar levels in both naive and activated T-cells. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. [provided by RefSeq]. |
| 免疫原 | KLH conjugated synthetic peptide: human IL-12RB2 |
| 抗原种属 | Human |
| 基因名称 | IL12RB2 |
| 基因ID | |
| 蛋白名称 | Interleukin-12 receptor subunit beta-2 |
| Uniprot ID | |
| 功能 | Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. |
| 分子量 | Theoretical: 95 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |