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Anti-S100A4 Antibody (9W585) 是一种 Rabbit 抗体,靶向 S100A4。Anti-S100A4 Antibody (9W585) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-S100A4 Antibody (9W585) 是一种 Rabbit 抗体,靶向 S100A4。Anti-S100A4 Antibody (9W585) 可用于 WB,ICC/IF,IHC,IP,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-S100A4 Antibody (9W585) is a Rabbit antibody targeting S100A4. Anti-S100A4 Antibody (9W585) can be used in WB,ICC/IF,IHC,IP,FCM. |
别名 | S100 calcium binding protein A4, PEL98, P9KA, MTS1, CAPL, 42A, 18A2 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. 2. Western blot analysis of S100A4 expression in A375 cell lysate. 3. Immunohistochemical analysis of paraffin-embedded Rat stomach, using the Antibody at 1:200 dilution. 4. Immunohistochemical analysis of paraffin-embedded Human lung adenocarcinoma, using the Antibody at 1:200 dilution. 5. Immunohistochemical analysis of paraffin-embedded Human thyroid cancer, using the Antibody at 1:200 dilution. 6. Immunohistochemical analysis of paraffin-embedded Human esophageal carcinoma, using the Antibody at 500 dilution. 7. Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using S100A4 Antibody. 8. Immunofluorescent analysis of HeLa cells, using S100A4 Antibody. |
应用 | |
推荐剂量 | WB: 1:1000-2000 IHC: 1:100-200 ICC/IF: 1:50-200 IP 1:20-50 FCM 1:20-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
研究背景 | The Mts1 gene encodes a small acidic Ca2+-binding protein, Mts1 (also designated S100A4, calvasculin or metastasin). Mts1 belongs to the S100 family of small Ca2+-binding proteins and is expressed in a cell-specific manner. Mts1 protein is involved in tumor progression and metastasis, and also has a significant stimulatory effect on angiogenesis. The level of Mts1 protein in serum increases with aging, suggesting that Mts1 may play a role in the ind-uction of tumor progression via stimulation of angiogenesis. In addition, Mts1 cooperates with p53 in apoptosis induction by binding to the C-term-inal regulatory domain of p53 to inhibit the DNA binding activity of p53. The ability of Mts1 to enhance p53-dependent apoptosis may accelerate the loss of p53 function in tumors. Thus, Mts1 can contribute to the development of a more aggressive phenotype during tumor progression. |
偶联 | Unconjugated |
免疫原 | A synthesized peptide: human S100A4 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 12 kDa. |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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