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Anti-FKBP12 Antibody (2Z412)
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产品编号 TMAC-01489
别名 PPIASE, PKCI2, PKC12, FKBP-1A, FKBP-12, FKBP12, FKBP1, FK506 binding protein 1A
Anti-FKBP12 Antibody (2Z412) 是一种 Rabbit 抗体，靶向 FKBP12。Anti-FKBP12 Antibody (2Z412) 可用于 WB,ICC/IF。
Anti-FKBP12 Antibody (2Z412)
Anti-FKBP12 Antibody (2Z412)
还可以产品编号 TMAC-01489 别名 PPIASE, PKCI2, PKC12, FKBP-1A, FKBP-12, FKBP12, FKBP1, FK506 binding protein 1A
Anti-FKBP12 Antibody (2Z412) 是一种 Rabbit 抗体，靶向 FKBP12。Anti-FKBP12 Antibody (2Z412) 可用于 WB,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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| 产品描述 | Anti-FKBP12 Antibody (2Z412) is a Rabbit antibody targeting FKBP12. Anti-FKBP12 Antibody (2Z412) can be used in WB,ICC/IF. |
| 别名 | PPIASE, PKCI2, PKC12, FKBP-1A, FKBP-12, FKBP12, FKBP1, FK506 binding protein 1A |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of FKBP12 on different cells lysates using anti-FKBP12 antibody at 1/500 dilution. Positive control: Line 1: SH-SY5Y, Line 2:V937. 2. ICC staining FKBP12 in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining FKBP12 in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining FKBP12 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; ICC/IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases which bind to and mediate the effects of immunosuppressive drugs such as Cyclosporin, FK506 and Rapamycin. FKBP12.6, also known as FK506-binding protein 1B, is a 108 amino acid immunophilin belonging to the FKBP-type PPIase family. Subcellularly localized to the cytoplasm, FKBP12.6 binds to RyR in cardiac muscle sarcoplasmic reticulum and possibly plays a unique physiological role in excitation-contraction coupling in cardiac muscle. FKBP12.6 also catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Ubiquitously expressed, FKBP12.6 is found at highest levels in brain and thymus. FKBP12.6 is expressed as two isoforms produced by alternative splicing. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 12 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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