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种类:Mouse Monoclonal
应用:WB,IHC-P,IHC-Fr,ICC/IF,IF
交叉反应:Human,Mouse (predicted:Rat)
种类:Mouse Monoclonal
应用:WB,IHC-P,IHC-Fr,ICC/IF,IF
交叉反应:Human,Mouse (predicted:Rat)

| 产品描述 | Anti-Acetyl-Histone H4 (Lys5) Antibody (8M508) is a Mouse antibody targeting Acetyl-Histone H4 (Lys5). Anti-Acetyl-Histone H4 (Lys5) Antibody (8M508) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 克隆号 | 8M508 |
| 交叉反应 | Human,Mouse (predicted:Rat) |
| 应用 | WBIHC-PIHC-FrICC/IFIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Nucleus. Chromosome. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Antigen affinity purification |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Jul 2008] |
| 基因名称 | H4C1 |
| 基因ID | |
| 蛋白名称 | Histone H4 |
| 功能 | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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