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Anti-HGF Antibody-HRP (2G808) 是一种 HRP-conjugated Rabbit 抗体,靶向 HGF。Anti-HGF Antibody-HRP (2G808) 可用于 ELISA。
Anti-HGF Antibody-HRP (2G808) 是一种 HRP-conjugated Rabbit 抗体,靶向 HGF。Anti-HGF Antibody-HRP (2G808) 可用于 ELISA。
产品描述 | Anti-HGF Antibody-HRP (2G808) is a HRP-conjugated Rabbit antibody targeting HGF. Anti-HGF Antibody-HRP (2G808) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2G808 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 0.1-1 μg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human HGF / Hepatocyte Growth Factor (rh HGF / Hepatocyte Growth Factor; NP_000592.3Met 1-Ser 728), conjugated with horseradish-peroxidase (HRP). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by mesenchymal cells as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility and matrix invasion give it a central role in angiogenesis, tumorogenesis, and tissue regeneration. HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF has no detectable protease activity. Defects in hepatocyte growth factor are the cause of deafness autosomal recessive type 39. A form of profound prelingual sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | HRP |
其他可选修饰符 | Unconjugated |
可提供抗体种类 | 2 |
免疫原 | Recombinant Human HGF / Hepatocyte Growth Factor protein |
抗原种属 | Human |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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