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Anti-CYP2D6 Polyclonal Antibody 2

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货号 TMAB-04885

Anti-CYP2D6 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CYP2D6。Anti-CYP2D6 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-CYP2D6 Polyclonal Antibody 2

Anti-CYP2D6 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-04885

Anti-CYP2D6 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CYP2D6。Anti-CYP2D6 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-CYP2D6 Polyclonal Antibody 2 is a Rabbit antibody targeting CYP2D6. Anti-CYP2D6 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Pig,Cow,Horse,Rabbit,Sheep,Cat)
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].
抗原信息
免疫原
KLH conjugated synthetic peptide: human CYP2D6
抗原种属
Human
基因名称
CYP2D6
基因ID
1565
蛋白名称
Cytochrome P450 2D6
Uniprot ID
P10635
功能
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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