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The two recurrent dominant mutations in RAB11B leading to a neurodevelopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protein mislocalization.

| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 5 μg | ¥ 493 | 6-8日内发货 | |
| 10 μg | ¥ 790 | 6-8日内发货 | |
| 20 μg | ¥ 1,330 | 5日内发货 | |
| 50 μg | ¥ 2,580 | 5日内发货 | |
| 100 μg | ¥ 5,170 | 5日内发货 | 
| 生物活性 | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. | 
| 产品描述 | The two recurrent dominant mutations in RAB11B leading to a neurodevelopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protein mislocalization. | 
| 种属 | Human | 
| 表达系统 | HEK293 Cells | 
| 标签 | N-His | 
| 蛋白编号 | ABQ59034.1 | 
| 别名 | RAB11B, member RAS oncogene family,H-YPT3 | 
| 蛋白构建 | A DNA sequence encoding the human RAB11B (ABQ59034.1) (Gly2-Cys215) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His | 
| 蛋白纯度 | > 95 % as determined by SDS-PAGE. | 
| 分子量 | 26.3 kDa (predicted) | 
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. | 
| 蛋白性状 | Lyophilized powder | 
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. | 
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. | 
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. | 
| 研究背景 | The two recurrent dominant mutations in RAB11B leading to a neurodevelopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protein mislocalization. |