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Anti-MSRB2 Polyclonal Antibody

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货号 TMAB-09040

Anti-MSRB2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MSRB2。Anti-MSRB2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MSRB2 Polyclonal Antibody

Anti-MSRB2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09040

Anti-MSRB2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MSRB2。Anti-MSRB2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-MSRB2 Polyclonal Antibody is a Rabbit antibody targeting MSRB2. Anti-MSRB2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion.
组织特异性Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Methionine is one of the most readily oxidized essential amino acids and an intermediate in the biosynthesis of cysteine, carnitine, taurine, lecithin, phosphatidylcholine and other phospholipids. In its oxidative state, Methionine is regulated in vivo by methionine sulfoxide reductases (Msr). MsrB2 is a 182 amino acid mitochondrial protein that is ubiquitously expressed. Belonging to the MsrB Met sulfoxide reductase family, MsrB2 acts as a catalyst for the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, MsrB2 is suggested to play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. MsrB2 utilizes zinc ions, one per subunit, as cofactors.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MSRB2
抗原种属
Human
基因名称
MSRB2
基因ID
22921
蛋白名称
Methionine-R-sulfoxide reductase B2, mitochondrial
Uniprot ID
Q9Y3D2
功能
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.
化学信息
分子量Theoretical: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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