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Anti-IL-24 Antibody (1H832)

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产品编号 TMAY-02301

Anti-IL-24 Antibody (1H832) 是一种 Rabbit 抗体,靶向 IL-24。Anti-IL-24 Antibody (1H832) 可用于 ELISA。

Anti-IL-24 Antibody (1H832)

Anti-IL-24 Antibody (1H832)

Rating icon 还可以
产品编号 TMAY-02301

Anti-IL-24 Antibody (1H832) 是一种 Rabbit 抗体,靶向 IL-24。Anti-IL-24 Antibody (1H832) 可用于 ELISA。

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产品介绍

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产品描述
Anti-IL-24 Antibody (1H832) is a Rabbit antibody targeting IL-24. Anti-IL-24 Antibody (1H832) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
1H832
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-24/MDA-7 (rh IL-24/MDA-7; NP_001172085.1; Met1-Leu207).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin-24 (IL-24) also known as Melanoma differentiation-associated gene 7 protein (MDA-7) is a member of the IL10 family of cytokines. IL-24/MDA-7/IL24 can induce apoptosis selectively in various cancer cells. Overexpression of IL-24 leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Human IL-24/MDA-7/IL24 is secreted by activated peripheral blood mononuclear cells and is the ligand for two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. Northern blot analysis revealed IL-24/MDA-7/IL24 expression in human tissues associated with the immune system such as the spleen, thymus, peripheral blood leukocytes, and normal melanocytes. IL-24/MDA-7/IL24 binding to either its endogenous receptors on human keratinocytes or to ectopically expressed receptors on baby hamster kidney cells leads to activation of the signal transducers and activators of transcription.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human IL-24/MDA-7 Protein
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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