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Anti-VE-Cadherin Antibody-FITC (2K899)
还可以产品编号 TMAY-00822F
Anti-VE-Cadherin Antibody-FITC (2K899) 是一种 FITC-conjugated Mouse 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody-FITC (2K899) 可用于 FCM。
Anti-VE-Cadherin Antibody-FITC (2K899)
Anti-VE-Cadherin Antibody-FITC (2K899)
还可以产品编号 TMAY-00822F
Anti-VE-Cadherin Antibody-FITC (2K899) 是一种 FITC-conjugated Mouse 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody-FITC (2K899) 可用于 FCM。
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| 产品描述 | Anti-VE-Cadherin Antibody-FITC (2K899) is a FITC-conjugated Mouse antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody-FITC (2K899) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2K899 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CD144 expression on HUVEC cells. Cells were stained with FITC-conjugated anti-Human CD144. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VE-Cadherin / CD144 / CDH5 (rh VE-Cadherin / CD144 / CDH5; CAA56306.1; Met1-Gln593) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human VE-Cadherin / CD144 / CDH5 Protein |
| 抗原种属 | Human |
| 研究领域 | Hemangioblast Markers, Cardiac Stem Cell Markers |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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