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Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191)

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Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191)
产品编号 TMAY-01541H

Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191) 是一种 HRP-conjugated Rabbit 抗体,靶向 Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F。Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191) 可用于 ELISA。

Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191)
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Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191)

Rating icon 还可以
Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191)
产品编号 TMAY-01541H

Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191) 是一种 HRP-conjugated Rabbit 抗体,靶向 Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F。Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191) 可用于 ELISA。

规格价格库存数量
20 μg
¥ 1,180
5日内发货
100 μg
¥ 3,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191) is a HRP-conjugated Rabbit antibody targeting Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F. Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody-HRP (1B191) can be used in ELISA.
Ig Type
Rabbit IgG
克隆号
1B191
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human respiratory syncytial virus (RSV) Fusion glycoprotein / RSV-F (TMPY-01078; P03420.1; Met1-Thr529) and was produced using recombinant antibody technology and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneumovirus of the family paramyxoviridae. Like other members of the family, HRSV has two major surface glycoproteins (G and F) that play important roles in the initial stages of the infectious cycle. The G protein mediates attachment of the virus to cell surface receptors, while the F protein promotes fusion of the viral and cellular membranes, allowing entry of the virus ribonucleoprotein into the cell cytoplasm. The fusion (F) protein of RSV is synthesized as a nonfusogenic precursor protein (F), which during its migration to the cell surface is activated by cleavage into the disulfide-linked F1 and F2 subunits. This fusion is pH independent and occurs directly at the outer cell membrane, and the F2 subunit was identifed as the major determinant of RSV host cell specificity. The trimer of F1-F2 interacts with glycoprotein G at the virion surface. Upon binding of G to heparan sulfate, the hydrophobic fusion peptide is unmasked and induces the fusion between host cell and virion membranes. Notably, RSV fusion protein is unique in that it is able to interact directly with heparan sulfate and therefore is sufficient for virus infection. Furthermore, the fusion protein is also able to trigger p53-dependent apoptosis.
偶联与修饰
偶联
HRP
抗原信息
免疫原
Recombinant Protein: Human respiratory syncytial virus (RSV) Fusion glycoprotein / RSV-F protein (TMPY-01078)
抗原种属
RSV
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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