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Anti-IL-6R Antibody (9I61) 是一种 Rabbit 抗体,靶向 IL-6R。Anti-IL-6R Antibody (9I61) 可用于 ELISA。
Anti-IL-6R Antibody (9I61) 是一种 Rabbit 抗体,靶向 IL-6R。Anti-IL-6R Antibody (9I61) 可用于 ELISA。
产品描述 | Anti-IL-6R Antibody (9I61) is a Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody (9I61) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9I61 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL6RA / CD126 (rM IL6RA; TMPY-01214; NP_034689.2; Ile 44-Glu 357). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse IL6RA protein (TMPY-01214) |
抗原种属 | Mouse |
研究领域 | Neuroinflammation |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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